The museum opened in 1918 and is located in a 16th-century mansion next to the Cathedral. After renovations, it reopened in 2012. The museum's museum program highlights the collection of Sacred Art and Faience. The Temporary Exhibition Room features an exhibition of paintings on Portalegre, featuring works by contemporary Portuguese painters such as Manuel d'Assumpção, João Tavares, Arsénio da Ressurreição, Benvindo Ceia, Abel Santos, and Miguel Barrias, among others.

The house where José Régio lived for 34 years, enrolled at the Mouzinho da Silveira High School in Portalegre. It began as a boarding house and was gradually acquired by the poet until he became the only guest. Here, you can admire some of the pieces the poet collected throughout his life. Among the collections, religious art sculptures and regional crafts stand out.

A museum dedicated to the presentation, conservation, and study of the Portalegre Tapestries. The name Guy Fino honors the person who actively contributed to Portugal's inclusion among the world's leading tapestry producers. On the ground floor, you can learn about the history of the Portalegre Tapestries manufacturing process and their technical execution techniques; on the upper floor, you'll find exclusive tapestry works presented chronologically.

Space where several cultural activities take place.

Colectividade criada com o objetivo de fomentar a recolha, sistematização e incentivo da prática de Jogos Tradicionais.

Space located in the convent of the Jesuits and former Royal Factory of Wool, where there are several cultural and social activities.

Library working at the Santa Clara Convent.

Small museum located in the Cathedral of Portalegre, where are exposed some of the most important pieces of religious art of the region.

Site with a vast documentary collection.