Cartaxo Cultural Centre, contemporary architecture, is a space open to the exterior, composed of two rooms of spectacles, that allow not only the display of cinema, but also the presentation of plays and dance shows and music. The Center develops an important work of artistic training and awareness. There is still room for temporary exhibitions and thematic conferences.

This project by the Catalan architect Josep Lluis Mateo stands out in the city center landscape for its innovative architecture. It is a hollow building, clad in metal and wood, with four floors. In addition to the exhibition spaces, it has a synthetic ice skating rink and an auditorium with 275 seats, equipped with a high-quality acoustic system, without the use of amplification systems.

A cultural centre located in the old market of Vila Real de Santo António. It has a large auditorium where several shows take place. There are also occasional painting and sculpture exhibitions.

It was named Coliseu Avenida from 1917 to 1950. It was recovered by the Town Hall in 2005. It maintains the same architecture but can now welcome all sorts of cultural events. It also has a museum that shows the island's past way of life.

Casa Roque Gameiro, built between 1898 and 1901, is currently open to the public and you can visit some of the rooms in the house, profusely decorated with tiles by Bordalo Pinheiro, as well as temporary exhibitions on the two lower floors.

This space intends to be a dynamic center for comics and other associated arts, such as illustration and animation cinema.

This is the biggest Paleolithic open-air museum, where you can view a variety of rock engravings. The most important rock art collections are those of Canada do Inferno, Penascosa, Ribeira de Piscos, Quinta da Barca, Pharisee and beech. It is classified as a national monument and Cultural heritage of humanity.

The Lethes Theater is named after a mythical river, whose waters had the power to erase life's annoyances and sadness from memory. A perfect name for a place where performance is used to entertain the spectators.

In this theater, in operation since 1999, take place the main cultural events of the city, from music to theater, through dance and poetry. It also organizes workshops, ateliers, temporary exhibitions and gatherings. There is also the "Canto do Teatro", a space dedicated to the memory of the former Teatro Viriato (Theatro Boa União), which operated between 1883 and 1960.

In a building donated by the Soares family, the Casa-Museum of the Mário Soares Foundation and the João Soares Cultural Center are located. In addition to the permanent exhibition, entitled "Portuguese 20th Century: The Paths of Democracy - João Soares / Mário Soares", there are other spaces that host temporary exhibitions, a library and other cultural initiatives.